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Cover Feature: Prebiotically Plausible Autocatalytic Peptide Amyloids (Chem. Eur. J. 3/2022)
Author(s) -
Rout Saroj K.,
Rhyner David,
Riek Roland,
Greenwald Jason
Publication year - 2022
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202104546
Subject(s) - peptide , autocatalysis , chemistry , combinatorial chemistry , amino acid , peptide sequence , cover (algebra) , function (biology) , stereochemistry , biochemistry , biology , catalysis , evolutionary biology , gene , mechanical engineering , engineering
Simple amino acids activated by the volcanic gas carbonyl sulfide can condense into peptides that then spontaneously assemble into amyloids. This suggests a plausible prebiotic relevance of peptide amyloids and has led to the discovery that they can template sequence‐selective, regioselective and stereoselective peptide synthesis. Depending on the environmental conditions, such amyloid templating can function in either complementary or self‐replicating mode. More information can be found in the Research Article by R. Riek, J. Greenwald, et al. (DOI: 10.1002/chem.202103841).