Open AccessFrom genome to function: systematic analysis of the soil bacterium Bacillus subtilis
Author(s) -
Harwood Colin R.,
Crawshaw Samuel G.,
Wipat Anil
Publication year - 2001
Publication title -
comparative and functional genomics
Language(s) - English
Resource type - Journals
eISSN - 1532-6268
pISSN - 1531-6912
DOI - 10.1002/cfg.69
Subject(s) - bacillus subtilis , genome , computational biology , function (biology) , bacteria , biology , microbiology and biotechnology , genetics , gene
Bacillus subtilis is a sporulating Gram‐positive bacterium that lives primarily in the soil and associated water sources. Whilst this bacterium has been studied extensively in the laboratory, relatively few studies have been undertaken to study its activity in natural environments. The publication of the B. subtilis genome sequence and subsequent systematic functional analysis programme have provided an opportunity to develop tools for analysing the role and expression of Bacillus genes in situ . In this paper we discuss analytical approaches that are being developed to relate genes to function in environments such as the rhizosphere. Copyright © 2001 John Wiley & Sons, Ltd.