MicroCore: mapping genome expression to cell pathways and networks | Zendy

Patel Manish | Zendy; Nagl Sylvia | Zendy

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MicroCore: mapping genome expression to cell pathways and networks

Author(s) -

Patel Manish,

Nagl Sylvia

Publication year - 2004

Publication title -

comparative and functional genomics

Language(s) - English

Resource type - Journals

eISSN - 1532-6268

pISSN - 1531-6912

DOI - 10.1002/cfg.362

Subject(s) - java , computer science , plug in , suite , visualization , open source , cluster analysis , data mining , computational biology , bioinformatics , programming language , software , biology , artificial intelligence , archaeology , history

The MicroCore toolkit is a suite of analysis programs for microarray and proteomics data that is open source and programmed exclusively in Java. MicroCore provides a flexible and extensible environment for the interpretation of functional genomics data through visualization. The first version of the application (downloadable from the MicroCore website: http://www.ucl.ac.uk/oncology/MicroCore/microcore.htm), implements two programs-PIMs (protein interaction maps) and MicroExpress-and is soon to be followed by an extended version which will also feature a fuzzy k-means clustering application and a Java-based R plug-in for microarray analysis. PIMs and MicroExpress provide a simple yet powerful way of graphically relating large quantities of expression data from multiple experiments to cellular pathways and biological processes in a statistically meaningful way.

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