Open AccessComputational aspects of protein functionality
Author(s) -
Paton R. C.,
Toh C.H.
Publication year - 2004
Publication title -
comparative and functional genomics
Language(s) - English
Resource type - Journals
eISSN - 1532-6268
pISSN - 1531-6912
DOI - 10.1002/cfg.360
Subject(s) - diagrammatic reasoning , relation (database) , computer science , function (biology) , metaphor , key (lock) , data science , data mining , biology , programming language , linguistics , genetics , philosophy , computer security
The purpose of this short article is to examine certain aspects of protein functionality with relation to some key organizing ideas. This is important from a computational viewpoint in order to take account of modelling both biological systems and knowledge of these systems. We look at some of the lexical dimensions of the function and how certain constructs can be related to underlying ideas. The pervasive computational metaphor is then discussed in relation to protein multifunctionality, and the specific case of von Willebrand factor as a ‘smart’ multifunctional protein is briefly considered. Some diagrammatic techniques are then introduced to better articulate protein function. Copyright © 2004 John Wiley & Sons, Ltd.