Open AccessMulticentre prospective cohort study of body mass index and postoperative complications following gastrointestinal surgery
Author(s) -
T M Drake,
Dmitri Nepogodiev,
Stephen J. Chapman,
James Glasbey,
Chetan Khatri,
Chia Yew Kong,
H A Claireaux,
Michael Bath,
Midhun Mohan,
Lisa McNamee,
Michael E. Kelly,
Harriet Mitchell,
J.E.F. Fitzgerald,
Ewen M. Harrison,
Aneel Bhangu,
Ioannis Antoniou,
R H Dean,
N Davies,
Shaun Trecarten,
Ian Henderson,
C Holmes,
Joanne Wylie,
RD Shuttleworth,
A Jindal,
F Hughes,
Pishoy Gouda,
Robert J. Fleck,
Michael Hanrahan,
K Priya Deepa Lakshmi,
J H Chen,
M. Sykes,
Rajiv K. Sethi,
Sukrit Suresh,
Prashant Patel,
Mulchand S. Patel,
Rick Varma,
Jameel Mushtaq,
Buket Gundogan,
William Bolton,
T Khan,
Josh Burke,
R Morley,
N. Favero,
R Adams,
V Thirumal,
Ewan D. Kennedy,
Kenneth Ong,
Yu-lin Tan,
Joseph Gabriel,
Ali Bakhsh,
Jillian Low,
A. Yener,
Vlad Paraoan,
Ryan Preece,
Thomas W Tilston,
Elspeth Cumber,
S Dean,
Talisa Ross,
Eleanor McCance,
H Amin,
L. Satterthwaite,
Keiran Clement,
Robert Gratton,
Edward David Mills,
Seehui Chiu,
GiunYi Hung,
N M Rafiq,
John Hayes,
K Robertson,
K Dynes,
Han-sheng Huang,
Shershah Assadullah,
Joseph W. Duncumb,
Richard Moon,
Stephanie Poo,
J.K. Mehta,
K R Joshi,
Rory Callan,
Joseph M. Norris,
Nicholas Chilvers,
Harry Keevil,
P Jull,
Shweta Mallick,
D. Elf,
Lucas J. Carr,
C. Player,
Eric Barton,
AnneLaure Martin,
S. G. Ratu,
Elizabeth Roberts,
Philippe Phan,
A Dyal,
John E. Rogers,
Andrew Henson,
Neil Reid,
Dermot Burke,
G. Culleton,
Sara Lynne,
S. Mansoor,
Caitlin W. Brennan,
R. Blessed,
Caroline L. Holloway,
A Hill,
Thomas Goldsmith,
Sharon Mackin,
S Kim,
Evelina Woin,
Gregory A. Brent,
John M. Coffin,
Oliver J. Ziff,
Z. Momoh,
R. K. Debenham,
Mohyadin Abdullahi Ahmed,
Chul Soon Yong,
Jonathan C. M. Wan,
Hannah C. Copley,
Pramin Raut,
Faraz Chaudhry,
G Nixon,
Charles J. Dorman,
Rose Tan,
S. Kanabar,
N. Canning,
M. Dolaghan,
N Bell,
M. McMenamin,
A. Chhabra,
Krika Duke,
L. Turner,
Tejal Patel,
L S Chew,
Mehdi Ali Mirza,
Surabhika Lunawat,
Babatunde Oremulé,
Nicholas T. Ward,
M. Anwar H. Khan,
E.T. Tan,
David H. MacLennan,
R McGregor,
Elizabeth Chisholm,
Emily Griffin,
L. Bell,
Beverly Hughes,
J. Davies,
H. Haq,
Hussien Ahmed,
N. Ungcharoen,
C. Whacha,
R. Thethi,
Rachel Markham,
Angeline Lee,
ER Batt,
Nicholas Bullock,
Claudia Francescon,
N. M. Shafiq,
Jiashi Zhao,
Sayinthen Vivekanantham,
Ishani Barai,
J. L. Allen,
Dominic C. Marshall,
Charlotte McIntyre,
Holly Wilson,
Anita Ashton,
C. Lek,
Nebil Behar,
M. DavisHall,
N. Seneviratne,
L. Esteve,
Mert Sirakaya,
S Ali,
Susan Pope,
Jaimo Ahn,
Anna Craig-Mcquaide,
W. A. Gatfield,
Sharon E. Leong,
A. M. Demetri,
A. L. Kerr,
Clare M. Rees,
K Loveday,
S Liu,
Maheshi Wijesekera,
Devina Maru,
Mark Attalla,
Nicholas A. Smith,
D. Brown,
P. Sritharan,
Apar Shah,
V. Charavanamuttu,
G Heppenstall-Harris,
Kelvin K. Ng,
T. Raghvani,
Neil Rajan,
Kate Hulley,
NJG Moody,
M. Williams,
A. Cotton,
Meedya Sharifpour,
Kaung Lwin,
Melissa A. Bright,
Abhishek Chitnis,
M Abdelhadi,
Akuilina Semana,
Franklin G. Morgan,
Rebecca Reid,
Joanne M. Dickson,
Lorinda Anderson,
Ronan McMullan,
N Ahern,
A. Asmadi,
Lillian Anderson,
J. Lua Boon Xuan,
Lauren Crozier,
S. McAleer,
David Lees,
AT Adebayo,
Manoj Kumar Das,
A Amphlett,
Arwa Mohammed AlRobeye,
Alice Valli,
Jessi Khangura,
A. Winarski,
Ahmed Ali,
Helen Woodward,
C. Gouldthrope,
Megan C. Turner,
K Sasapu,
Michael Tonkins,
Jonathan Wild,
Mark W. Robinson,
J. Hardie,
R. Heminway,
Ruth Narramore,
N. Ramjeeawon,
A. D. Hibberd,
F. Winslow,
W Ho,
Benjamin F. Chong,
Kyung-Taek Lim,
Samuel B. Ho,
J. A. Crewdson,
S. Singagireson,
Neeraj Kalra,
Foteini Koumpa,
H. I. Jhala,
Wai Cheong Soon,
Monil Karia,
Michael Greshan Rasiah,
Diamantis Xylas,
H. M. Gilbert,
M. SundarSingh,
J Wills,
Sobia Akhtar,
Suhani S. Patel,
Hu Liu,
C Brathwaite-Shirley,
H. Nayee,
Oreekha Amin,
T. Rangan,
Eleanor Jane Turner,
Catherine McCrann,
Robert P. Shepherd,
N Patel,
J. PrestSmith,
E. Auyoung,
A. Murtaza,
Amy Coates,
O. PrysJones,
Martin S. King,
Sarah Gaffney,
Charlotte Dewdney,
I. Nehikhare,
Jessica A. Lavery,
John Bassett,
Kelvin J.A. Davies,
K. Ahmad,
A Collins,
Meghan Acres,
Christine Egerton,
Karen Y. Cheng,
X Chen,
Nicholas Chan,
A Sheldon,
S. Khan,
J. Empey,
Emily Ingram,
Ashish Malik,
Marianne Johnstone,
R. Goodier,
Jigar Shah,
Julian Giles,
Jules A.A. Sanders,
Stewart McLure,
S. Pal,
A. Rangedara,
A Baker,
C. A. Asbjoernsen,
C. Girling,
Lincoln Gray,
L. Gauntlett,
C Joyner,
Sajid Qureshi,
Yogendra Praveen Mogan,
James Ng,
Arepalli Kumar,
James H. Park,
David Chi Hau Tan,
Kong-Bong Choo,
Kausalya Raman,
P. Buakuma,
Chengwu Xiao,
S. Govinden,
Olof Thompson,
M. Charalambos,
Elliot John Brown,
Rickesh Bharat Karsan,
Tara Dogra,
Laetitia Bullman,
Peter Dawson,
Arthur L. Frank,
H. Abid,
Lin Tung,
Umer Qureshi,
A. Tahmina,
Brian W. Matthews,
R. Harris,
A. O'Connor,
K. Mazan,
Sundas Iqbal,
Sophie Stanger,
Jill D. Thompson,
Jacqueline A. Sullivan,
E. Uppal,
Ann Macaskill,
F. A. Bamgbose,
Christieophytou,
Ashley Carroll,
C. W. Rookes,
Uttaran Datta,
Amrita Dhutia,
S. Rashid,
N. Ahmed,
T. Lo,
Shivam Bhanderi,
Christopher Blore,
S Ahmed,
H. J. Shaheen,
S Abburu,
S Majid,
Zainab Abbas,
Sutopa Talukdar,
Laura Burney,
Jayna Patel,
Ossama AlObaedi,
Andrew W. Roberts,
S Mahboob,
Bhagwan D. Singh,
Sameer A. Sheth,
Priyesh Karia,
A Prabhudesai,
Kelvin Kow,
Kantida Koysombat,
S Wang,
P. J. Morrison,
Y. Maheswaran,
Pearse A. Keane,
Phillip Correia Copley,
O. Brewster,
Guofeng Xu,
P G Harries,
Carmel Wall,
A Al-Mousawi,
S. Bonsu,
Pedro Cunha,
Thomas Ward,
Jerry Paul,
K. Nadanakumaran,
Salim Tayeh,
H. Holyoak,
J Remedios,
K Theodoropoulou,
A. Luhishi,
Louis Jacob,
Fang Long,
Andrew Atayi,
Safdar Sarwar,
Olive Parker,
J. Harvey,
Heather Ross,
Ritika Rampal,
George Thomas,
Piyush Vanmali,
Catherine C. McGowan,
John C. Stein,
Valerie J. Robertson,
L. Carthew,
Vannesa Yue May Teng,
J. Fong,
Anne Street,
Clare Thakker,
Derek O’Reilly,
Mauro Bravo,
Aline Cecília Pizzolato,
Haseeb Anwar Khokhar,
M. J. Ryan,
Lindsay Cheskes,
Rebecca Carr,
Abdelmonim Salih,
S. Bassiony,
Ryan K. C. Yuen,
David Chrastek,
H O’Sullivan,
Adaugo Amajuoyi,
A Wang,
O. Sitta,
J. Wye,
Mubasher A. Qamar,
Carol Major,
Anjali Kaushal,
Catrin Morgan,
Maurizio Petrarca,
R Allot,
Karan Verma,
Shoma Dutt,
Chrissie Chilima,
S. Peroos,
S Kosasih,
Hyung-Min Chin,
L. Ashken,
Rupert M. Pearse,
Robert O'Loughlin,
A Me,
Kavindra Singh,
Joel Norton,
Rohitkumar Patel Sagar,
Nikesh Jathanna,
L Rothwell,
Nicholas Watson,
Floyd E. Harding,
PierreAndré Dubé,
Hassan Khalid,
N Punjabi,
Markus Sagmeister,
Paul Gill,
S. Shahid,
Sarah Hudson-Phillips,
Daniel George,
J. Scott Ashwood,
Thomas Lewis,
Mahesh Shanker Dhar,
P. Sangal,
I. A. Rhema,
Deevia Kotecha,
Zeeshan Afzal,
J. A. Syeed,
Esha Prakash,
P. Jalota,
J Herron,
Lawrence M Kimani,
A. Delport,
Ayushi Shukla,
V Agarwal,
S. Parthiban,
Harshad Thakur,
W Cymes,
S Rinkoff,
Jennifer Turnbull,
Muhammad Hayat,
S. Darr,
UA Khan,
J Lim,
A. Higgins,
Gokul R Lakshmipathy,
B. Forte,
E. Canning,
A. Jaitley,
Jeffrey P. Lamont,
Ethan Toner,
Ali Ghaffar,
M. McDowell,
Dominique Salmon,
Orla O’Carroll,
A Khan,
Kevin Clesham,
C Palmer,
Ronan A Lyons,
Andrew M. Bell,
Robin Chin,
Ronan Waldron,
A Zachary Trimble,
Sharon E. Cox,
Umair Ashfaq,
John Campbell,
Rachel Holliday,
George P. McCabe,
F Morris,
R. Priestland,
Olivia Ver,
A. Ledsam,
Rachel Vaughan,
D Lim,
Zoe Bakewell,
Rebecca Hughes,
Renol Koshy,
Hunter Jackson,
P Narayan,
Anita Cardwell,
C. L. Jubainville,
T Arif,
Lucy Elliott,
Vidushi Gupta,
Gayathri Bhaskaran,
Adenike Odeleye,
Fadia Thamir Ahmed,
Reena Shah,
Joe Pickard,
Yasir Suleman,
Alexander S. North,
Liusaidh McClymont,
N Hussain,
I. Ibrahim,
Guat Shi Ng,
Vincent WaiSun Wong,
Alison E Lim,
Lyndsay N. Harris,
T. Tharmachandirar,
Devender Mittapalli,
Vimal Patel,
M. Lakhani,
H.Z. Bazeer,
Vishal Narwani,
Kulmeet Sandhu,
L Wingfield,
Sarah Gentry,
Helena Adjei,
Muhammad Iqbal Bhatti,
L. Braganza,
J. Barnes,
Sabuj Kanti Mistry,
Gauri Chillarge,
Samantha Stokes,
J. Cleere,
Saman Wadanamby,
A.M. Bucko,
James Meek,
Naomi Boxall,
Emily G. Heywood,
Joanne Wiltshire,
C. Toh,
Alex Ward,
Badrun Shurovi,
Dillon Horth,
Brij Patel,
B Ali,
T. Spencer,
T Axelson,
L Kretzmer,
C. Chhina,
C Anandarajah,
Tessa Fautz,
Carolyn Horst,
A. A. Thevathasan,
J Q Ng,
F. Hirst,
C. Fred Brewer,
Andrew Logan,
Joseph Lockey,
Paul Forrest,
Nigel Keelty,
A.D. Wood,
Laurie Rigueros Springford,
Pascale Avery,
Therese Schulz,
T. P. Bemand,
Lara Howells,
Hailey Collier,
Apoorva Khajuria,
Ravi Tharakan,
Sarah Parsons,
Alice Buchan,
Rachel McGalliard,
J Mason,
Olivia Cundy,
Ni Li,
Natalie Redgrave,
R P Watson,
Theodore Pezas,
Y Dennis,
E. Segall,
Mansoor Hameed,
Angelica Lynch,
M. C. Chamberlain,
Fraser S Peck,
Yan Ning Neo,
George H. Russell,
M Elseedawy,
S Lee,
Naomi Foster,
Youn Soo,
L. Puan,
Richard Dennis,
Harshita Goradia,
A Qureshi,
S. Osman,
Thomas Reeves,
L. Dinsmore,
M Marsden,
Qun Lu,
T. PittsTucker,
C.E. Dunn,
R Walford,
E. Jenny Heathcote,
Robert C.G. Martin,
Agamem Pericleous,
K. Brzyska,
Kern Reid,
Nick Wetherall,
Eilish McAleer,
D. Thomas,
R S Kiff,
Stephanie Milne,
M Holmes,
J Bartlett,
José Luís Carvalho,
T. Bloomfield,
F. Tongo,
Ronald Bremner,
Yong Ning,
B. A. Atraszkiewicz,
A. Mehdi,
Muhammad Rizwan Tahir,
G. X. J. Sherliker,
Anne Tear,
A. Pandey,
A. Broyd,
Hisham Omer,
Martine Raphaël,
Wahid Chaudhry,
Shayan Shahidi,
Ali S M Jawad,
C Gill,
Ingo Fisher,
I. Adeleja,
Ian Clark,
G Aidoo-Micah,
Philip Stather,
Gazbar Salam,
Thomas Glover,
Gavin Deas,
Nicholas Keyi Sim,
Rhalumi Daniel Obute,
William Wynell-Mayow,
Mohammed Salik Sait,
N. Mitha,
G Bernier,
Muhammad Bilal Siddiqui,
Raghav Shaunak,
A Wali,
Gavin Cuthbert,
Roshni Bhudia,
Elizabeth M. Webb,
Suken A. Shah,
Nabila Ansari,
M. Thamara P. R. Perera,
N. Kelly,
Ross McAllister,
Guy Stanley,
Colm Keane,
Veeranna Shatkar,
C Maxwell-Armstrong,
L A Henderson,
Natalie Maple,
R Manson,
Ryan Adams,
Elisabeth Semple,
Marcos Mills,
Ahmed Daoub,
A. Marsh,
A. Ramnarine,
J. Hartley,
M. Malaj,
Paul Jewell,
E.A. Whatling,
N Hitchen,
M Chen,
Brian K. P. Goh,
J. Fern,
Sophie Rogers,
L.F. Derbyshire,
David Robertson,
N. Abuhussein,
Praveena Deekonda,
Peter Harrison,
L. Aildasani,
Hannah Turley,
Mohamed Sherif,
G Pandey,
Joseph Filby,
Andrew J. Johnston,
Mohamed Farah Yusuf Mohamud,
Kajal Gohil,
Albert Tsui,
Ritu Singh,
Shujing Jane Lim,
K P O'Sullivan,
L. L. McKelvey,
Stephen O’Neill,
H.F. Roberts,
Steven R. Brown,
Yun-Ping Cao,
R Buckle,
YewWah Liew,
Samuel S. Y. Sii,
Chiara Ventre,
Christopher J Graham,
T. Filipescu,
A. Yousif,
Reetika Dawar,
Andrea Wright,
Miriam Peters,
Rebecca Varley,
Slawomir Owczarek,
Simon Hartley,
Mohammed Khattak,
Atif Iqbal,
M Ali,
B. Durrani,
Yajur Narang,
George Bethell,
L. Horne,
R. Pinto,
Kathy Nicholls,
Ivan Kisyov,
Hew D.T. Torrance,
William English,
Shan Lakhani,
Syed Faaz Ashraf,
Mary L Venn,
V. Elangovan,
Zehra Kazmi,
J. Brecher,
Shyam Sukumar,
Adnan Mastan,
Alice E Mortimer,
Jennifer Parker,
J Boyle,
M Elkawafi,
Jeffrey M. Beckett,
Ajay Mohite,
Aditya Narain,
Eshan Mazumdar,
A. Sreh,
A. Hague,
David V. Weinberg,
Laura A. Fletcher,
Malcolm Steel,
H. Shufflebotham,
Mariam Masood,
Yash Sinha,
Cara Jenvey,
H. Kitt,
R Slade,
Ashley Craig,
Ciara Deall,
T. Reakes,
Jordan V. Chervenkoff,
E Strange,
Moira K. O’Bryan,
Charlotte Murkin,
Deepika Joshi,
T. Bergara,
S. Naqib,
D. Wylam,
S. Scotcher,
Christopher Hewitt,
Michael Stoddart,
Ashwin Kerai,
Adam Joseph Trist,
Stephanie Cole,
Cathryn Knight,
Simon Stevens,
Graham Cooper,
Rory Ingham,
Jon Dobson,
Alexandra C. O’Kane,
J. Moradzadeh,
Allyson Duffy,
C. Henderson,
C. McLaughin,
Toby Hoskins,
R Reehal,
Lucy R. Bookless,
Ross McLean,
Elaine J. Stone,
Esther Wright,
H Abdikadir,
Charlotte Roberts,
O Spence,
Mukunthan Srikantharajah,
Eduardo Ruiz,
J. H. Matthews,
Elizabeth C. Gardner,
E. Kelly Hester,
Prasheeran,
R Simpson,
Muhammad Saeed Minhas,
Emily F. Cornish,
Sahar Semnani,
Djamila Rojoa,
A Radotra,
John Eraifej,
K. Eparh,
Daniel MajorSmith,
Bhavin Mistry,
Siobhan Hickling,
W. Din,
ChunJen Liu,
P. Mithrakumar,
V. Mirdavoudi,
Madeeha Rashid,
Clare McGenity,
O Hussain,
M. Kadicheeni,
Hannah Gardner,
N. AnimAddo,
J Pearce,
Alec Aslanyan,
Chara Ntala,
T. Sorah,
J. Parkin,
M. Alizadeh,
Amanda B. White,
F. Edozie,
J.H. Johnston,
A.G. Abdul Kahar,
V. Navayogaarajah,
Derrius Carter,
Parisa Khonsari,
Andrea Burgess,
Arachchige Ponweera,
A. Cody,
Yongsheng Tan,
Anthony YKC Ng,
A. Croall,
Catherine K. Allan,
S Ng,
V. Raghuvir,
Richard J. Telfer,
Andrew D. Greenhalgh,
Caroline McKerr,
Marie Alexandra Edison,
B A Patel,
Keith L. Dear,
Myra Hardy,
P Williams,
S Hassan,
Uzma Sajjad,
E. O’Neill,
Sandra Lopes,
Laura Healy,
Nadim El Jamal,
S Tan,
D. Lazenby,
S. B. Husnoo,
S. Beecroft,
T. Sarvanandan,
Christina G. Weston,
N Bassam,
S. Rabinthiran,
Umar Hayat,
Lauren Ng,
D. Varma,
Mohamad Anas Sukkari,
Ajmal Mian,
Abeer Omar,
J W Kim,
J. Sellathurai,
Javed Iqbal Mahmood,
Casey L. O’Connell,
Ruma Bose,
Helen Heneghan,
Peter Lalor,
Jesse Matheson,
Colin P. Doherty,
Caroline Cullen,
D. James Cooper,
Sophia Angelov,
C. Drislane,
Andrew C. Smith,
A. Kreibich,
Ebrahim Palkhi,
Andrya J. Durr,
Andrew Lotfallah,
David Gold,
Erin L. McKean,
A. Dhanji,
A. Anilkumar,
Amitabh Thacoor,
Zahid Hameed Siddiqui,
Shir Lynn Lim,
A. Piquet,
Shelly Anderson,
Darren McCormack,
Jayati Gulati,
Arwa Ibrahim,
Scott Murray,
Stewart Walsh,
Anika L. McGrath,
Paul Ziprin,
Eddy Chua,
Chong-yang Lou,
Joseph R. Bloomer,
Heidi Paine,
Denise OseiKuffour,
Carla White,
A Szczap,
Shyam Gokani,
Kirtan Patel,
M. K. Malys,
A. Reed,
G. E. Torlot,
A. Charania,
Siddique Ahmad,
Niraj Varma,
H Cheema,
L. Austreng,
H. Petra,
M Chaudhary,
Menen Zegeye,
Enders K. Ng,
D. Coffey,
R. S. Heer,
Sweta Singh,
E. Seager,
S. Cumming,
Rishi Suresh,
Sumita Verma,
Imogen Ptacek,
Adam Gwozdz,
Tianqin Yang,
Ayush Khetarpal,
Syed Shumon,
Thomas Fung,
W. Leung,
P. Kwang,
Ling Chew,
Wayren Loke,
Alan J. Curran,
Carlos H.F. Chan,
Christine McGarrigle,
Sean P. Cullen,
Enoch Wong,
Conor Toale,
D. Collins,
Niamh Keane,
Bryan J. Traynor,
D. Shanahan,
A. Yan,
Daniyal J. Jafree,
C Topham,
Stefan Mitrasinovic,
Sharif Omara,
G Bingham,
Panagis M. Lykoudis,
B.H. Miranda,
Katharine Whitehurst,
G. Kumaran,
Yadsan Devabalan,
Humaira Aziz,
M. Shoa,
Shiva Dindyal,
J Yates,
Inge Bernstein,
Gilad Rattan,
Rachael Coulson,
S. Stezaker,
A Isaac,
Menatalla Salem,
Angela McBride,
H. McFarlane,
L. Yow,
J. S. Macdonald,
Richard D. Bartlett,
S. Turaga,
Ursula White,
Wan Jane Liew,
Nicholas H. Yim,
Andrew Ang,
Andrew Simpson,
Daniel F. McAuley,
E Craig,
Lorna Murphy,
P. Shepherd,
Jim Kee,
A. Abdulmajid,
Arlene E. Chung,
H. L. Warwick,
Alana Livesey,
Patrick Holton,
Mark D Theodoreson,
S. L. Jenkin,
J. Turner,
Jonathan Entwisle,
Stéphane Marchal,
S. O'Connor,
Harry Blege,
Joanna M S Aithie,
Leh Sabine,
G. E. Stewart,
S. Jackson,
A. Kishore,
C. M. Lankage,
Frank Acquaah,
Holly Joyce,
K McKevitt,
Calvin Coffey,
A. Fawaz,
Katelyn Dolbec,
Donnchadh O’Sullivan,
J M Geraghty,
Eric Lim,
Linda Burnes Bolton,
David Fitzpatrick,
Caitlin Robinson,
T. Ramtoola,
Sophie Collinson,
Lisa Grundy,
Paul McEnhill,
Gurvinder Singh Harbhajan Singh,
Dafydd Loughran,
David Golding,
Rachel Keeling,
Robert P. Williams,
Robert Whitham,
Sangeetha Yoganathan,
R. Nachiappan,
Richard Egan,
Raisah Owasil,
Marilyn L. Kwan,
Aina He,
R. Goh,
Rahul Bhome,
Penelope J. Teoh,
K. Raji,
Nimeshi Jayakody,
J. Matthams,
Jaron Chong,
C Y Luk,
Robert Greig,
Matthew Trail,
George Charalambous,
Alistair Rocke,
N. Gardiner,
F. A. Bulley,
Nicole Warren,
Emma Brennan,
P. Fergurson,
R. Wilson,
Heather Whittingham,
Elizabeth Brown,
Rashmi Khanijau,
K. Gandhi,
Shaine A. Morris,
Adam Boulton,
Nakul Chandan,
A. E. Barthorpe,
R. Maamari,
Shahneen Sandhu,
Michael McCann,
Lawrence M. Higgs,
V Balian,
Craig B. Reeder,
Charles Diaper,
T. A. Sale,
H Ali,
Carolyn Archer,
A K Clarke,
Joseph Heskin,
Penelope Hurst,
Jack D. Farmer,
Lauren O’Flynn,
Long Doan,
B A Shuker,
G. Stott,
Nethmi Vithanage,
Katie Hoban,
P.N. Nesargikar,
Hilary Kennedy,
Cathleen Grossart,
Eunicia Tan,
Chloe Roy,
Peng Yong Sim,
K.E. Leslie,
D. Eastern Kang Sim,
Mehtap Haktanır Abul,
N. Cody,
Andrea Tay,
E Woon,
S. Sng,
Jin Jiun Mah,
John Robson,
Eathar Shakweh,
Victoria C. Wing,
Harriet L. Mills,
Mimi Li,
Tina Barrow,
Sathyan Balaji,
Helen Jordan,
C. Phillips,
Hania Naveed,
Shashivadan P. Hirani,
Aswan Tai,
Raguprakash Ratnakumaran,
A. Sahathevan,
Ahmed Mohamed Abdel Shafì,
Mohamed Seedat,
Rupert Weaver,
A Batho,
R. Punj,
Haran Selvachandran,
Nilesh Bhatt,
S. Botchey,
Z. Khonat,
Kiva Brennan,
Charlotte Morrison,
E Devlin,
Andrea Linton,
Elizabeth Galloway,
Susan McGarvie,
Norma K.C. Ramsay,
Hayden McRobbie,
H Whewell,
William H. Dean,
S. Nelaj,
Mazin Eragat,
Ashutosh Mishra,
T Kane,
Mohamed Zuhair,
Mary Wells,
David Wilkinson,
Neil Woodcock,
Erwei Sun,
N. Ahmad Aziz,
M. K. Abd Ghaffar
Publication year - 2016
Publication title -
british journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.202
H-Index - 201
eISSN - 1365-2168
pISSN - 0007-1323
DOI - 10.1002/bjs.10203
Subject(s) - medicine , overweight , body mass index , confidence interval , odds ratio , prospective cohort study , obesity , cohort study , complication , cohort , surgery , logistic regression , malignancy
Background There is currently conflicting evidence surrounding the effects of obesity on postoperative outcomes. Previous studies have found obesity to be associated with adverse events, but others have found no association. The aim of this study was to determine whether increasing body mass index ( BMI ) is an independent risk factor for development of major postoperative complications. Methods This was a multicentre prospective cohort study across the UK and Republic of Ireland. Consecutive patients undergoing elective or emergency gastrointestinal surgery over a 4‐month interval (October–December 2014) were eligible for inclusion. The primary outcome was the 30‐day major complication rate (Clavien–Dindo grade III –V). BMI was grouped according to the World Health Organization classification. Multilevel logistic regression models were used to adjust for patient, operative and hospital‐level effects, creating odds ratios ( ORs ) and 95 per cent confidence intervals (c.i.). Results Of 7965 patients, 2545 (32·0 per cent) were of normal weight, 2673 (33·6 per cent) were overweight and 2747 (34·5 per cent) were obese. Overall, 4925 (61·8 per cent) underwent elective and 3038 (38·1 per cent) emergency operations. The 30‐day major complication rate was 11·4 per cent (908 of 7965). In adjusted models, a significant interaction was found between BMI and diagnosis, with an association seen between BMI and major complications for patients with malignancy (overweight: OR 1·59, 95 per cent c.i. 1·12 to 2·29, P = 0·008; obese: OR 1·91, 1·31 to 2·83, P = 0·002; compared with normal weight) but not benign disease (overweight: OR 0·89, 0·71 to 1·12, P = 0·329; obese: OR 0·84, 0·66 to 1·06, P = 0·147). Conclusion Overweight and obese patients undergoing surgery for gastrointestinal malignancy are at increased risk of major postoperative complications compared with those of normal weight.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom