Acute Arthritis Complicating Rubella Vaccination
Author(s) -
Thompson George R.,
Ferreyra Alfredo,
Brackett Robert G.
Publication year - 1971
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/art.1780140104
Subject(s) - medicine , polyarthritis , vaccination , arthritis , carpal tunnel syndrome , rubella vaccine , rubella , pediatrics , surgery , immunology , measles
After a field trial of rubella virus vaccine (HPV‐77 DK 12 strain), 329 children (2.8%) developed joint symptoms. Forty had complete rheumatologic evaluation and constitute the basis of this report. Twenty children (50%) had predominantly knee complaints; 13 (33%) had symptoms suggesting the carpal tunnel syndrome; and 7 (17%) had polyarthritis. The mean duration of arthritis was 18.4 days, and the mean interval between vaccination and onset of arthritis was 30.6 days.
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