Open AccessMetacarpophalangeal pattern profile analysis in Sotos syndrome
Author(s) -
Butler Merlin G.,
Meaney F. John,
Kittur Smita,
Hersh Joseph H.,
Hornstein Lusia,
Opitz John M.,
Reynolds James F.
Publication year - 1985
Publication title -
american journal of medical genetics
Language(s) - English
Resource type - Journals
eISSN - 1096-8628
pISSN - 0148-7299
DOI - 10.1002/ajmg.1320200408
Subject(s) - sotos syndrome , medicine , pediatrics
The metacarpophalangeal pattern profile (MCPP) was analyzed on 16 Sotos syndrome patients. A mean Sotos syndrome profile was produced. Correlation studies confirm clinical homogeneity of Sotos syndrome individuals. Discriminant analysis of Sotos syndrome patients and normal individuals produces a function of two MCPP variables and age, which may provide a useful tool for diagnosis.