Open AccessAn Air Particulate Pollutant Induces Neuroinflammation and Neurodegeneration in Human Brain Models (Adv. Sci. 21/2021)
Author(s) -
Kang You Jung,
Tan HsihYin,
Lee Charles Y.,
Cho Hansang
Publication year - 2021
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202170145
Subject(s) - neuroinflammation , neurodegeneration , particulates , human health , pollutant , human brain , air pollutants , cover (algebra) , microglia , neuroscience , environmental science , medicine , biology , immunology , environmental health , pathology , air pollution , disease , ecology , engineering , inflammation , mechanical engineering
Human Brain Model In article number 2101251 by Hansang Cho and co‐workers, PM2.5‐polluted human brain models (PMBs) are created in a 3D microfluidic platform reconstituting key aspects of human brain immunity under the PM2.5 exposure. The cover artwork shows the potential risk of neuroinflammation on brain health induced by air pollutants from diesel exhaust. Cover illustration by You Jung Kang. CT images of organs kindly provided by NIH.