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Analyzing Shotgun Proteomic Data with PatternLab for Proteomics
Author(s) -
Carvalho Paulo C.,
Yates III John R.,
Barbosa Valmir C.
Publication year - 2010
Publication title -
current protocols in bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.535
H-Index - 57
eISSN - 1934-340X
pISSN - 1934-3396
DOI - 10.1002/0471250953.bi1313s30
Subject(s) - shotgun proteomics , proteomics , shotgun , computer science , gene ontology , ontology , graphical user interface , interface (matter) , computational biology , state (computer science) , biology , gene , programming language , gene expression , genetics , operating system , philosophy , epistemology , bubble , maximum bubble pressure method
PatternLab for proteomics is a one‐stop shop computational environment for analyzing shotgun proteomic data. Its modules provide means to pinpoint proteins/peptides that are differentially expressed and those that are unique to a state. It can also cluster the ones that share similar expression profiles in time‐course experiments, as well as help in interpreting results according to Gene Ontology. PatternLab is user‐friendly, simple, and provides a graphical user interface. Curr. Protoc. Bioinform . 30:13.13.1‐13.13.15. © 2010 by John Wiley & Sons, Inc.