Open AccessUsing Cloud Computing Infrastructure with CloudBioLinux, CloudMan, and Galaxy
Author(s) -
Afgan Enis,
Chapman Brad,
Jadan Margita,
Franke Vedran,
Taylor James
Publication year - 2012
Publication title -
current protocols in bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.535
H-Index - 57
eISSN - 1934-340X
pISSN - 1934-3396
DOI - 10.1002/0471250953.bi1109s38
Subject(s) - cloud computing , computer science , interface (matter) , graphical user interface , converged infrastructure , world wide web , galaxy , operating system , set (abstract data type) , utility computing , distributed computing , cloud computing security , astrophysics , physics , bubble , maximum bubble pressure method , programming language
Cloud computing has revolutionized availability and access to computing and storage resources, making it possible to provision a large computational infrastructure with only a few clicks in a Web browser. However, those resources are typically provided in the form of low‐level infrastructure components that need to be procured and configured before use. In this unit, we demonstrate how to utilize cloud computing resources to perform open‐ended bioinformatic analyses, with fully automated management of the underlying cloud infrastructure. By combining three projects, CloudBioLinux, CloudMan, and Galaxy, into a cohesive unit, we have enabled researchers to gain access to more than 100 preconfigured bioinformatics tools and gigabytes of reference genomes on top of the flexible cloud computing infrastructure. The protocol demonstrates how to set up the available infrastructure and how to use the tools via a graphical desktop interface, a parallel command‐line interface, and the Web‐based Galaxy interface. Curr. Protoc. Bioinform . 38:11.9.1‐11.9.20. © 2012 by John Wiley & Sons, Inc.