Open AccessGenome Annotation and Curation Using MAKER and MAKER‐P
Author(s) -
Campbell Michael S.,
Holt Carson,
Moore Barry,
Yandell Mark
Publication year - 2014
Publication title -
current protocols in bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.535
H-Index - 57
eISSN - 1934-340X
pISSN - 1934-3396
DOI - 10.1002/0471250953.bi0411s48
Subject(s) - annotation , genome , computer science , computational biology , genome project , coding (social sciences) , gene , information retrieval , biology , genetics , artificial intelligence , statistics , mathematics
This unit describes how to use the genome annotation and curation tools MAKER and MAKER‐P to annotate protein‐coding and noncoding RNA genes in newly assembled genomes, update/combine legacy annotations in light of new evidence, add quality metrics to annotations from other pipelines, and map existing annotations to a new assembly. MAKER and MAKER‐P can rapidly annotate genomes of any size, and scale to match available computational resources. © 2014 by John Wiley & Sons, Inc.