Open AccessExploring Genetic, Genomic, and Phenotypic Data at the Rat Genome Database
Author(s) -
Laulederkind Stanley J. F.,
Hayman G. Thomas,
Wang ShurJen,
Lowry Timothy F.,
Nigam Rajni,
Petri Victoria,
Smith Jennifer R.,
Dwinell Melinda R.,
Jacob Howard J.,
Shimoyama Mary
Publication year - 2012
Publication title -
current protocols in bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.535
H-Index - 57
eISSN - 1934-340X
pISSN - 1934-3396
DOI - 10.1002/0471250953.bi0114s40
Subject(s) - database , biology , phenotype , genome , model organism , computational biology , organism , human genome , disease , gene , genetics , computer science , medicine , pathology
The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, http://rgd.mcw.edu) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes, and cellular components for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat.