Open AccessUsing the DFCI Gene Index Databases for Biological Discovery
Author(s) -
Antonescu Corina,
Antonescu Valentin,
Sultana Razvan,
Quackenbush John
Publication year - 2010
Publication title -
current protocols in bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.535
H-Index - 57
eISSN - 1934-340X
pISSN - 1934-3396
DOI - 10.1002/0471250953.bi0106s29
Subject(s) - identifier , gene , database , gene ontology , index (typography) , information retrieval , biological database , sequence database , computer science , biology , computational biology , world wide web , bioinformatics , genetics , gene expression , programming language
The DFCI Gene Index Web pages provide access to analyses of ESTs and gene sequences for nearly 114 species, as well as a number of resources derived from these. Each species‐specific database is presented using a common format with a home page. A variety of methods exist that allow users to search each species‐specific database. Methods implemented currently include nucleotide or protein sequence queries using WU‐BLAST, text‐based searches using various sequence identifiers, searches by gene, tissue and library name, and searches using functional classes through Gene Ontology assignments. This protocol provides guidance for using the Gene Index Databases to extract information. Curr. Protoc. Bioinform . 29:1.6.1‐1.6.36. © 2010 by John Wiley & Sons, Inc.