Open AccessMethods to Measure Olfactory Behavior in Mice
Author(s) -
Zou Junhui,
Wang Wenbin,
Pan YungWei,
Lu Song,
Xia Zhengui
Publication year - 2015
Publication title -
current protocols in toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.449
H-Index - 23
eISSN - 1934-9262
pISSN - 1934-9254
DOI - 10.1002/0471140856.tx1118s63
Subject(s) - olfaction , habituation , psychology , odor , olfactory system , olfactory memory , neuroscience , associative learning , cognitive psychology , sociality , olfactory bulb , biology , ecology , central nervous system
Mice rely on the sense of olfaction to detect food sources, recognize social and mating partners, and avoid predators. Many behaviors of mice, including learning and memory, social interaction, fear, and anxiety are closely associated with their function of olfaction, and behavior tasks designed to evaluate those brain functions may use odors as cues. Accurate assessment of olfaction is not only essential for the study of olfactory system but also critical for proper interpretation of various mouse behaviors, especially learning and memory, emotionality and affect, and sociality. Here we describe a series of behavior experiments that offer multidimensional and quantitative assessments for mouse olfactory function, including olfactory habituation, discrimination, odor preference, odor detection sensitivity, and olfactory memory, with respect to both social and nonsocial odors. © 2015 by John Wiley & Sons, Inc.