Effect of Low-Dose Supplementation of Arginine Vasopressin on Need for Blood Product Transfusions in Patients With Trauma and Hemorrhagic Shock | Zendy

Carrie A. Sims | Zendy; Daniel N. Holena | Zendy; Patrick Kim | Zendy; José L. Pascual | Zendy; Brian P. Smith | Zendy; Niels D. Martin | Zendy; Mark J. Seamon | Zendy; Adam M. Shiroff | Zendy; Shariq Raza | Zendy; Lewis J. Kaplan | Zendy; Elena Grill | Zendy; Nicole Zimmerman | Zendy; Christopher Mason | Zendy; Benjamin S. Abella | Zendy; Patrick M. Reilly | Zendy

Open Access

Effect of Low-Dose Supplementation of Arginine Vasopressin on Need for Blood Product Transfusions in Patients With Trauma and Hemorrhagic Shock

Author(s) -

Carrie A. Sims,

Daniel N. Holena,

Patrick Kim,

José L. Pascual,

Brian P. Smith,

Niels D. Martin,

Mark J. Seamon,

Adam M. Shiroff,

Shariq Raza,

Lewis J. Kaplan,

Elena Grill,

Nicole Zimmerman,

Christopher Mason,

Benjamin S. Abella,

Patrick M. Reilly

Publication year - 2019

Publication title -

jama surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.757

H-Index - 176

eISSN - 2168-6262

pISSN - 2168-6254

DOI - 10.1001/jamasurg.2019.2884

Subject(s) - medicine , vasopressin , resuscitation , anesthesia , blood volume , blood product , blood pressure , placebo , shock (circulatory) , surgery , alternative medicine , pathology

Current therapies for traumatic blood loss focus on hemorrhage control and blood volume replacement. Severe hemorrhagic shock, however, is associated with a state of arginine vasopressin (AVP) deficiency, and supplementation of this hormone may decrease the need for blood products in resuscitation.

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