Assessment of Anti–Factor Xa Levels of Patients Undergoing Colorectal Surgery Given Once-Daily Enoxaparin Prophylaxis
Author(s) -
Christopher J. Pannucci,
Kory I. Fleming,
Corinne Bertolaccini,
Ann Marie Prazak,
Lyen C. Huang,
T. Bartley Pickron
Publication year - 2019
Publication title -
jama surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.757
H-Index - 176
eISSN - 2168-6262
pISSN - 2168-6254
DOI - 10.1001/jamasurg.2019.1165
Subject(s) - medicine , colorectal surgery , enoxaparin sodium , guideline , randomized controlled trial , surgery , venous thromboembolism , clinical trial , anesthesia , abdominal surgery , low molecular weight heparin , heparin , thrombosis , pathology
Between 4% and 12% of patients undergoing colorectal surgery and receiving enoxaparin, 40 mg per day, have a postoperative venous thromboembolism (VTE) event. An improved understanding of why "breakthrough" VTE events occur despite guideline-compliant prophylaxis is an important patient safety question.
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