Open AccessEvaluation of Military Use of Tranexamic Acid and Associated Thromboembolic Events
Author(s) -
Luke R. Johnston,
Carlos J. Rodríguez,
Eric A. Elster,
Matthew J. Bradley
Publication year - 2017
Publication title -
jama surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.757
H-Index - 176
eISSN - 2168-6262
pISSN - 2168-6254
DOI - 10.1001/jamasurg.2017.3821
Subject(s) - medicine , tranexamic acid , medline , medical emergency , intensive care medicine , surgery , blood loss , political science , law
Since publication of the CRASH-2 and MATTERs studies, the US military has included tranexamic acid (TXA) in clinical practice guidelines. While TXA was shown to decrease mortality in trauma patients requiring massive transfusion, improper administration and increased risk of venous thromboembolism remain a concern.
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