Use of Protamine for Anticoagulation During Carotid Endarterectomy | Zendy

Kariewhall | Zendy; Elizabeth C. Saunders | Zendy; Robin J. Larson | Zendy; David H. Stone | Zendy; Philip P. Goodney | Zendy

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Use of Protamine for Anticoagulation During Carotid Endarterectomy

Author(s) -

Kariewhall,

Elizabeth C. Saunders,

Robin J. Larson,

David H. Stone,

Philip P. Goodney

Publication year - 2015

Publication title -

jama surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.757

H-Index - 176

eISSN - 2168-6262

pISSN - 2168-6254

DOI - 10.1001/jamasurg.2015.3592

Subject(s) - medicine , carotid endarterectomy , stroke (engine) , protamine sulfate , meta analysis , relative risk , observational study , clinical trial , protamine , confidence interval , heparin , surgery , stenosis , mechanical engineering , engineering

Protamine sulfate can be administered at the conclusion of carotid endarterectomy (CEA) to reverse the anticoagulant effects of heparin and to limit the risk for postoperative bleeding. Protamine use remains controversial owing to concern for increased thrombotic complications with its use.

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