Association Between Specific Mutations inKRASCodon 12 and Colorectal Liver Metastasis | Zendy

Georgios Antonios Margonis | Zendy; Yuhree Kim | Zendy; Gaya Spolverato | Zendy; Aslam Ejaz | Zendy; Rohan Gupta | Zendy; David Cosgrove | Zendy; Robert A. Anders | Zendy; Georgios Karagkounis | Zendy; Michael A. Choti | Zendy; Timothy M. Pawlik | Zendy

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Association Between Specific Mutations inKRASCodon 12 and Colorectal Liver Metastasis

Author(s) -

Georgios Antonios Margonis,

Yuhree Kim,

Gaya Spolverato,

Aslam Ejaz,

Rohan Gupta,

David Cosgrove,

Robert A. Anders,

Georgios Karagkounis,

Michael A. Choti,

Timothy M. Pawlik

Publication year - 2015

Publication title -

jama surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.757

H-Index - 176

eISSN - 2168-6262

pISSN - 2168-6254

DOI - 10.1001/jamasurg.2015.0313

Subject(s) - kras , medicine , hazard ratio , colorectal cancer , oncology , retrospective cohort study , gastroenterology , mutation , metastasis , perioperative , cancer , gene , surgery , confidence interval , genetics , biology

Currently, one of the most commonly available biomarkers in the treatment of patients with colorectal liver metastases (CRLM) is the Kirsten rat sarcoma viral oncogene homolog (KRAS); however, the prognostic implications of specific mutations of the KRAS gene are still not well defined.

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