Intraoperative Fluorescence Imaging for Sentinel Lymph Node Detection | Zendy

Ingo Stoffels | Zendy; Joachim Dissemond | Zendy; Thorsten Pöppel | Zendy; Dirk Schadendorf | Zendy; Joachim Klode | Zendy

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Intraoperative Fluorescence Imaging for Sentinel Lymph Node Detection

Author(s) -

Ingo Stoffels,

Joachim Dissemond,

Thorsten Pöppel,

Dirk Schadendorf,

Joachim Klode

Publication year - 2015

Publication title -

jama surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.757

H-Index - 176

eISSN - 2168-6262

pISSN - 2168-6254

DOI - 10.1001/jamasurg.2014.3502

Subject(s) - medicine , indocyanine green , sentinel lymph node , lymph , melanoma , gamma probe , lymph node , sentinel node , radiology , surgery , breast cancer , lymphatic system , technetium , nuclear medicine , cancer , pathology , cancer research

The metastatic status of regional lymph nodes is the most relevant prognostic factor in breast cancer, melanoma, and other solid organ tumors with a lymphatic spread. The current gold standard for detection and targeted excision of the sentinel lymph node is preoperative lymphoscintigraphy with technetium Tc 99m. Because of the worldwide shortage of technetium Tc 99m, physicians are looking for nonradioactive dyes for sentinel lymph node labeling. Based on several retrospective studies, the fluorescent dye indocyanine green is considered a possible alternative to technetium Tc 99m.

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