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Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression
Author(s) -
Nikolaos Koutsouleris,
Dominic Dwyer,
Franziska Degenhardt,
Carlo Maj,
Maria Fernanda Urquijo-Castro,
Rachele Sanfelici,
David Popovic,
Oemer Faruk Oeztuerk,
Shalaila S. Haas,
Johanna Weiske,
Anne Ruef,
Lana KambeitzIlankovic,
Linda A. Antonucci,
Susanne Neufang,
Christian Schmidt-Kraepelin,
Stephan Ruhrmann,
Nora Penzel,
Joseph Kambeitz,
Theresa Haidl,
Marlene Rosen,
Katharine Chisholm,
Anita RiecherRössler,
Laura Egloff,
André Schmidt,
Christina Andreou,
Jarmo Hietala,
Timo Schirmer,
Georg Romer,
Petra Walger,
Maurizia Franscini,
Nina TraberWalker,
Benno G. Schimmelmann,
Rahel Flückiger,
Chantal Michel,
Wulf Rössler,
Oleg Borisov,
Peter Krawitz,
Karsten Heekeren,
Roman Buechler,
Christos Pantelis,
Peter Falkai,
Raimo K. R. Salokangas,
Rebekka Lencer,
Alessandro Bertolino,
Stefan Borgwardt,
Markus M. Nöethen,
Paolo Brambilla,
Stephen J. Wood,
Rachel Upthegrove,
Frauke SchultzeLutter,
Anastasia Theodoridou,
Eva Meisenzahl
Publication year - 2020
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2020.3604
Subject(s) - neurocognitive , generalizability theory , psychosis , schizophrenia (object oriented programming) , depression (economics) , neuroimaging , sample size determination , prodrome , psychology , medicine , psychiatry , clinical psychology , cognition , developmental psychology , statistics , mathematics , economics , macroeconomics
Diverse models have been developed to predict psychosis in patients with clinical high-risk (CHR) states. Whether prediction can be improved by efficiently combining clinical and biological models and by broadening the risk spectrum to young patients with depressive syndromes remains unclear.

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