Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders
Author(s) -
Daniel B. Rosoff,
George Davey Smith,
Falk W. Lohoff
Publication year - 2020
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2020.3554
Subject(s) - mendelian randomization , medicine , psychiatry , major depressive disorder , anxiety , population , genome wide association study , observational study , odds ratio , clinical psychology , mood , single nucleotide polymorphism , biochemistry , chemistry , environmental health , genetic variants , genotype , gene
Growing evidence suggests that prescription opioid use affects depression and anxiety disorders; however, observational studies are subject to confounding, making causal inference and determining the direction of these associations difficult.
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