Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell–Derived Cerebral Organoids in Schizophrenia | Zendy

Annie Kathuria | Zendy; Kara Lopez-Lengowski | Zendy; Smita Jagtap | Zendy; Donna L. McPhie | Zendy; Roy H. Perlis | Zendy; Bruce M. Cohen | Zendy; Rakesh Karmacharya | Zendy

Open Access

Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell–Derived Cerebral Organoids in Schizophrenia

Author(s) -

Annie Kathuria,

Kara Lopez-Lengowski,

Smita Jagtap,

Donna L. McPhie,

Roy H. Perlis,

Bruce M. Cohen,

Rakesh Karmacharya

Publication year - 2020

Publication title -

jama psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.531

H-Index - 365

eISSN - 2168-6238

pISSN - 2168-622X

DOI - 10.1001/jamapsychiatry.2020.0196

Subject(s) - induced pluripotent stem cell , transcriptome , organoid , biology , schizophrenia (object oriented programming) , gene expression profiling , neuroscience , gene expression , gene , genetics , medicine , psychiatry , embryonic stem cell

Three-dimensional cerebral organoids generated from patient-derived induced pluripotent stem cells (iPSCs) may be used to interrogate cellular-molecular underpinnings of schizophrenia.

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