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Association Between P300 Responses to Auditory Oddball Stimuli and Clinical Outcomes in the Psychosis Risk Syndrome
Author(s) -
Holly Hamilton,
Brian J. Roach,
Peter Bachman,
Ayşenil Belger,
Ricardo E. Carrión,
Erica Duncan,
Jason Johannesen,
Gregory A. Light,
Margaret Niznikiewicz,
Jean Addington,
Carrie E. Bearden,
Kristin S. Cadenhead,
Barbara A. Cornblatt,
Thomas H. McGlashan,
Diana O. Perkins,
Larry J. Seidman,
Ming T. Tsuang,
Elaine F. Walker,
Scott W. Woods,
Tyrone D. Can,
Daniel H. Mathalon
Publication year - 2019
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2019.2135
Subject(s) - prodrome , p3b , p3a , psychosis , audiology , schizophrenia (object oriented programming) , event related potential , psychology , medicine , electroencephalography , psychiatry
In most patients, a prodromal period precedes the onset of schizophrenia. Although clinical criteria for identifying the psychosis risk syndrome (PRS) show promising predictive validity, assessment of neurophysiologic abnormalities in at-risk individuals may improve clinical prediction and clarify the pathogenesis of schizophrenia.

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