Open AccessEffect of Adjunctive Estradiol on Schizophrenia Among Women of Childbearing Age
Author(s) -
Mark Weiser,
Linda Levi,
Daisy Zamora,
Anat Biegon,
John Paul SanGiovanni,
Michael Davidson,
Shimon Burshtein,
Ilan Gonen,
Paull Radu,
Kristina Slobozean Pavalache,
Igor Nastas,
Rina Hemi,
Timothy Ryan,
John M. Davis
Publication year - 2019
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2019.1842
Subject(s) - interquartile range , randomized controlled trial , positive and negative syndrome scale , medicine , schizoaffective disorder , placebo , schizophrenia (object oriented programming) , psychosis , psychiatry , alternative medicine , pathology
Several lines of evidence suggest that estradiol influences the course of schizophrenia, and a previous randomized controlled trial demonstrated that transdermal estradiol improved symptoms in female patients of childbearing age. However, many initial positive findings in schizophrenia research are not later replicated.
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