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Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression
Author(s) -
Ella Daly,
Madhukar H. Trivedi,
Adam Janik,
Honglan Li,
Yun Zhang,
Xiang Li,
Rosanne Lane,
Pilar Lim,
A. Duca,
David Hough,
Michael E. Thase,
John Zajecka,
Andrew Winokur,
Ilona Divacka,
Andrea Fagiolini,
Wiesław Jerzy Cubała,
István Bitter,
Pierre Blier,
Richard C. Shelton,
Patricio Molero,
Husseini K. Manji,
Wayne C. Drevets,
Jaskaran Singh
Publication year - 2019
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2019.1189
Subject(s) - nasal spray , medicine , placebo , antidepressant , treatment resistant depression , randomized controlled trial , anesthesia , depression (economics) , nasal administration , pharmacology , alternative medicine , macroeconomics , pathology , hippocampus , economics
Controlled studies have shown short-term efficacy of esketamine for treatment-resistant depression (TRD), but long-term effects remain to be established.

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