DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons | Zendy

O. Jovanova | Zendy; Ivaedeljković | Zendy; Derek Spieler | Zendy; Rosie M. Walker | Zendy; Chunyu Liu | Zendy; Michelle Luciano | Zendy; Jan Bressler | Zendy; Jennifer A. Brody | Zendy; Amanda J. Drake | Zendy; Kathryn L. Evans | Zendy; Rahul Gondalia | Zendy; Sonja Kunze | Zendy; Brigitte Kühnel | Zendy; Jari Lahti | Zendy; Rozenn N. Lemaître | Zendy; Riccardo E. Marioni | Zendy; Brenton R. Swenson | Zendy; Jayandra J. Himali | Zendy; Hongsheng Wu | Zendy; Yun Li | Zendy; Allan F. McRae | Zendy; Tom C. Russ | Zendy; James D. Stewart | Zendy; Zhiying Wang | Zendy; Guosheng Zhang | Zendy; KarlHeinz Ladwig | Zendy; André G. Uitterlinden | Zendy; Xiuqing Guo | Zendy; Annette Peters | Zendy; Katri Räikkönen | Zendy; John M. Starr | Zendy; Mélanie Waldenberger | Zendy; Naomi R. Wray | Zendy; Eric A. Whitsel | Zendy; a Sotoodehnia | Zendy; Sudha Seshadri | Zendy; David J. Porteous | Zendy; Joyce B. J. van Meurs | Zendy; Thomas H. Mosley | Zendy; Andrew M. McIntosh | Zendy; Michael Mendelson | Zendy; Daniel Levy | Zendy; Lifang Hou | Zendy; Johan G. Eriksson | Zendy; Myriam Fornage | Zendy; Ian J. Deary | Zendy; Andrea Baccarelli | Zendy; Henning Tiemeier | Zendy; Najaf Amin | Zendy

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DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons

Author(s) -

O. Jovanova,

Ivaedeljković,

Derek Spieler,

Rosie M. Walker,

Chunyu Liu,

Michelle Luciano,

Jan Bressler,

Jennifer A. Brody,

Amanda J. Drake,

Kathryn L. Evans,

Rahul Gondalia,

Sonja Kunze,

Brigitte Kühnel,

Jari Lahti,

Rozenn N. Lemaître,

Riccardo E. Marioni,

Brenton R. Swenson,

Jayandra J. Himali,

Hongsheng Wu,

Yun Li,

Allan F. McRae,

Tom C. Russ,

James D. Stewart,

Zhiying Wang,

Guosheng Zhang,

KarlHeinz Ladwig,

André G. Uitterlinden,

Xiuqing Guo,

Annette Peters,

Katri Räikkönen,

John M. Starr,

Mélanie Waldenberger,

Naomi R. Wray,

Eric A. Whitsel,

a Sotoodehnia,

Sudha Seshadri,

David J. Porteous,

Joyce B. J. van Meurs,

Thomas H. Mosley,

Andrew M. McIntosh,

Michael Mendelson,

Daniel Levy,

Lifang Hou,

Johan G. Eriksson,

Myriam Fornage,

Ian J. Deary,

Andrea Baccarelli,

Henning Tiemeier,

Najaf Amin

Publication year - 2018

Publication title -

jama psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.531

H-Index - 365

eISSN - 2168-6238

pISSN - 2168-622X

DOI - 10.1001/jamapsychiatry.2018.1725

Subject(s) - epigenome , dna methylation , depression (economics) , methylation , depressive symptoms , population , genetics , gene , biology , medicine , psychiatry , cognition , gene expression , macroeconomics , environmental health , economics

Depressive disorders arise from a combination of genetic and environmental risk factors. Epigenetic disruption provides a plausible mechanism through which gene-environment interactions lead to depression. Large-scale, epigenome-wide studies on depression are missing, hampering the identification of potentially modifiable biomarkers.

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