Open AccessAssociation of Prenatal Exposure to Population-Wide Folic Acid Fortification With Altered Cerebral Cortex Maturation in Youths
Author(s) -
Hamdi Eryilmaz,
Kevin Dowling,
Charlie Huntington,
Anais Rodriguez-Thompson,
Thomas W. Soare,
Lauren M. Beard,
Hang Lee,
Jeffrey C. Blossom,
Randy L. Gollub,
Ezra Susser,
Ruben C. Gur,
Monica E. Calkins,
Raquel E. Gur,
Theodore D. Satterthwaite,
Joshua L. Roffman
Publication year - 2018
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2018.1381
Subject(s) - medicine , observational study , pediatrics , cohort , cohort study , retrospective cohort study , population , magnetic resonance imaging , environmental health , radiology
Presently, 81 countries mandate the fortification of grain products with folic acid to lessen the risk of neural tube defects in the developing fetus. Epidemiologic data on severe mental illness suggest potentially broader effects of prenatal folate exposure on postnatal brain development, but this link remains unsubstantiated by biological evidence.
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