Skin Conductance Responses and Neural Activations During Fear Conditioning and Extinction Recall Across Anxiety Disorders
Author(s) -
MarieFrance Marin,
Rachel G. Zsido,
Huijin Song,
Natasha B. Lasko,
William D. S. Killgore,
Scott L. Rauch,
Naomi M. Simon,
Mohammed R. Milad
Publication year - 2017
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2017.0329
Subject(s) - anxiety , psychology , panic disorder , extinction (optical mineralogy) , specific phobia , ventromedial prefrontal cortex , generalized anxiety disorder , clinical psychology , fear conditioning , anxiety disorder , major depressive disorder , prefrontal cortex , psychiatry , cognition , mood , paleontology , biology
The fear conditioning and extinction neurocircuitry has been extensively studied in healthy and clinical populations, with a particular focus on posttraumatic stress disorder. Despite significant overlap of symptoms between posttraumatic stress disorder and anxiety disorders, the latter has received less attention. Given that dysregulated fear levels characterize anxiety disorders, examining the neural correlates of fear and extinction learning may shed light on the pathogenesis of underlying anxiety disorders.
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