Open AccessNature of Glutamate Alterations in Schizophrenia
Author(s) -
Kate Merritt,
Alice Egerton,
Matthew J. Kempton,
Matthew Taylor,
Philip McGuire
Publication year - 2016
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2016.0442
Subject(s) - schizophrenia (object oriented programming) , glutamate receptor , psychosis , glutamine , glutamatergic , medicine , schizoaffective disorder , psychology , basal ganglia , psychiatry , neuroscience , central nervous system , biology , biochemistry , receptor , amino acid
Alterations in glutamatergic neurotransmission may be fundamental to the pathophysiology of schizophrenia, and the glutamatergic system is a target for novel therapeutic interventions in the disorder.
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