Self-harm, Unintentional Injury, and Suicide in Bipolar Disorder During Maintenance Mood Stabilizer Treatment | Zendy

Joseph Hayes | Zendy; Alexandra Pitman | Zendy; Louise Marston | Zendy; Kate Walters | Zendy; John Geddes | Zendy; Michael King | Zendy; David Osborn | Zendy

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Self-harm, Unintentional Injury, and Suicide in Bipolar Disorder During Maintenance Mood Stabilizer Treatment

Author(s) -

Joseph Hayes,

Alexandra Pitman,

Louise Marston,

Kate Walters,

John Geddes,

Michael King,

David Osborn

Publication year - 2016

Publication title -

jama psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.531

H-Index - 365

eISSN - 2168-6238

pISSN - 2168-622X

DOI - 10.1001/jamapsychiatry.2016.0432

Subject(s) - mood stabilizer , quetiapine , bipolar disorder , olanzapine , psychiatry , lithium (medication) , poison control , mood , medicine , lamotrigine , psychology , schizophrenia (object oriented programming) , medical emergency , epilepsy

Self-harm is a prominent cause of morbidity in patients with bipolar disorder and is strongly associated with suicide. There is evolving evidence that lithium use may reduce suicidal behavior, in addition to concerns that the use of anticonvulsants may increase self-harm. Information is limited about the effects of antipsychotics when used as mood stabilizer treatment. Rates of unintentional injury are poorly defined in bipolar disorder, and understanding drug associations with this outcome may shed light on mechanisms for lithium's potential antisuicidal properties through reduction in impulsive aggression.

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