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Exome Sequencing of Familial Bipolar Disorder
Author(s) -
Fernando S. Goes,
Mehdi Pirooznia,
Jennifer Parla,
Melissa Kramer,
Elena Ghiban,
Senem Mavruk,
Yun-Ching Chen,
Eric T. Monson,
Virginia L. Willour,
Rachel Karchin,
Matthew Flickinger,
Adam E. Locke,
Shawn Levy,
Laura J. Scott,
Michael Boehnke,
Eli Stahl,
Jennifer L. Moran,
Christina M. Hultman,
Mikael Landén,
Shaun Purcell,
Pamela Sklar,
Peter P. Zandi,
W. Richard McCombie,
James B. Potash
Publication year - 2016
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2016.0251
Subject(s) - exome sequencing , genetics , bipolar disorder , biology , autism , exome , multiplex , gene , mutation , medicine , psychiatry , cognition , neuroscience
Complex disorders, such as bipolar disorder (BD), likely result from the influence of both common and rare susceptibility alleles. While common variation has been widely studied, rare variant discovery has only recently become feasible with next-generation sequencing.

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