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Hydromorphone Compared With Diacetylmorphine for Long-term Opioid Dependence
Author(s) -
Eugenia OviedoJoekes,
Daphne Guh,
Suzanne Brissette,
Kirsten Marchand,
Scott Macdonald,
Kurt Lock,
Scott Harrison,
Amin Janmohamed,
Aslam H. Anis,
Michael Krausz,
David C. Marsh,
Martin T. Schechter
Publication year - 2016
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2016.0109
Subject(s) - hydromorphone , medicine , heroin , opioid , randomized controlled trial , opioid use disorder , anesthesia , pharmacology , drug , receptor
Diacetylmorphine hydrochloride (the active ingredient in heroin), delivered under supervision, is effective for the treatment of severe opioid use disorder. However, owing to political and regulatory barriers, it is not available in many settings around the world, which limits the options for many long-term street opioid injectors not attracted into or retained in available treatments.

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