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Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks
Author(s) -
Richard Sherva,
Qian Wang,
Henry R. Kranzler,
Hongyu Zhao,
Ryan Koesterer,
Aryeh I. Herman,
Lindsay A. Farrer,
Joel Gelernter
Publication year - 2016
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2016.0036
Subject(s) - genome wide association study , medicine , cannabis , addiction , substance dependence , single nucleotide polymorphism , psychiatry , genetics , biology , genotype , gene
Cannabis dependence (CAD) is a serious problem worldwide and is of growing importance in the United States because cannabis is increasingly available legally. Although genetic factors contribute substantially to CAD risk, at present no well-established specific genetic risk factors for CAD have been elucidated.

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