Structural Brain Connectivity as a Genetic Marker for Schizophrenia | Zendy

Marc M. Bohlken | Zendy; Rachel M. Brouwer | Zendy; René C.W. Mandl | Zendy; Martijn P. van den Heuvel | Zendy; Anna M. Hedman | Zendy; Marc D. Binder | Zendy; Wiepke Cahn | Zendy; René S. Kahn | Zendy; Hilleke E. Hulshoff Pol | Zendy

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Structural Brain Connectivity as a Genetic Marker for Schizophrenia

Author(s) -

Marc M. Bohlken,

Rachel M. Brouwer,

René C.W. Mandl,

Martijn P. van den Heuvel,

Anna M. Hedman,

Marc D. Binder,

Wiepke Cahn,

René S. Kahn,

Hilleke E. Hulshoff Pol

Publication year - 2015

Publication title -

jama psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.531

H-Index - 365

eISSN - 2168-6238

pISSN - 2168-622X

DOI - 10.1001/jamapsychiatry.2015.1925

Subject(s) - schizophrenia (object oriented programming) , white matter , twin study , fractional anisotropy , diffusion mri , psychology , neuroscience , medicine , genetics , psychiatry , biology , magnetic resonance imaging , heritability , radiology

Schizophrenia is accompanied by a loss of integrity of white matter connections that compose the structural brain network, which is believed to diminish the efficiency of information transfer among brain regions. However, it is unclear to what extent these abnormalities are influenced by the genetic liability for developing the disease.

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