Interaction of theADRB2Gene Polymorphism With Childhood Trauma in Predicting Adult Symptoms of Posttraumatic Stress Disorder
Author(s) -
Israel Liberzon,
Anthony P. King,
Kerry J. Ressler,
Lynn M. Almli,
Peng Zhang,
T. Sean,
Gregory H. Cohen,
Marijo Tamburrino,
Joseph R. Calabrese,
Sandro Galea
Publication year - 2014
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2014.999
Subject(s) - cohort , single nucleotide polymorphism , traumatic stress , psychology , psychiatry , psychopathology , psychological trauma , cohort study , clinical psychology , medicine , genetics , biology , genotype , gene
Posttraumatic stress disorder (PTSD), while highly prevalent (7.6% over a lifetime), develops only in a subset of trauma-exposed individuals. Genetic risk factors in interaction with trauma exposure have been implicated in PTSD vulnerability.
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