Childhood Maltreatment, Altered Limbic Neurobiology, and Substance Use Relapse Severity via Trauma-Specific Reductions in Limbic Gray Matter Volume | Zendy

Nicholas T. Van Dam | Zendy; Kenneth Rando | Zendy; Marc N. Potenza | Zendy; Keri Tuit | Zendy; Rajita Sinha | Zendy

Open Access

Childhood Maltreatment, Altered Limbic Neurobiology, and Substance Use Relapse Severity via Trauma-Specific Reductions in Limbic Gray Matter Volume

Author(s) -

Nicholas T. Van Dam,

Kenneth Rando,

Marc N. Potenza,

Keri Tuit,

Rajita Sinha

Publication year - 2014

Publication title -

jama psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.531

H-Index - 365

eISSN - 2168-6238

pISSN - 2168-622X

DOI - 10.1001/jamapsychiatry.2014.680

Subject(s) - subiculum , psychiatry , substance dependence , psychology , substance abuse , neuroimaging , lingual gyrus , addiction , clinical psychology , comorbidity , medicine , dentate gyrus , hippocampus , cognition

Substance use disorders (SUDs) are among the most common sequelae of childhood maltreatment, yet the independent contributions of SUDs and childhood maltreatment to neurobiological changes and the effect of the latter on relapse risk (a critical variable in addiction treatment) are relatively unknown.

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