z-logo
open-access-imgOpen Access
Cognitive Decline Preceding the Onset of Psychosis in Patients With 22q11.2 Deletion Syndrome
Author(s) -
Jacob Vorstman,
Elemi Breetvelt,
Sasja N. Duijff,
Stéphan Eliez,
Maude Schneider,
Maria Jalbrzikowski,
Marco Armando,
Stefano Vicari,
Vandana Shashi,
Stephen R. Hooper,
Eva W.C. Chow,
Wai Lun Alan Fung,
Nancy J. Butcher,
Donald A. Young,
Donna M. McDonaldMcGinn,
Annick Vogels,
Thérèse van Amelsvoort,
Doron Gothelf,
Ronnie Weinberger,
Abraham Weizman,
Petra Klaassen,
Sanne Koops,
Wendy R. Kates,
Kevin M. Antshel,
Tony J. Simon,
Opal Ousley,
Ann Swillen,
Raquel E. Gur,
Carrie E. Bearden,
René S. Kahn,
Anne S. Bassett
Publication year - 2015
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2014.2671
Subject(s) - intelligence quotient , psychosis , psychiatry , psychology , schizophrenia (object oriented programming) , wechsler adult intelligence scale , pediatrics , cohort , longitudinal study , cognitive decline , global assessment of functioning , cognition , medicine , dementia , disease , pathology
Patients with 22q11.2 deletion syndrome (22q11DS) have an elevated (25%) risk of developing schizophrenia. Recent reports have suggested that a subgroup of children with 22q11DS display a substantial decline in cognitive abilities starting at a young age.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom