Neuroanatomical Characteristics Associated With Response to Dorsal Anterior Cingulotomy for Obsessive-Compulsive Disorder
Author(s) -
Garrett P. Banks,
Charles B. Mikell,
Brett E. Youngerman,
Bryan Henriques,
Kathleen Kelly,
Andrew K. Chan,
Diana García del Barco Herrera,
Darin D. Dougherty,
Emad N. Eskandar,
Sameer A. Sheth
Publication year - 2014
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2014.2216
Subject(s) - anterior cingulate cortex , grey matter , lesion , magnetic resonance imaging , laterality , cingulate cortex , diffusion mri , psychology , voxel , fractional anisotropy , voxel based morphometry , medicine , neuroscience , radiology , white matter , surgery , central nervous system , cognition
Approximately 10% of patients with obsessive-compulsive disorder (OCD) have symptoms that are refractory to pharmacologic and cognitive-behavioral therapies. Neurosurgical interventions can be effective therapeutic options in these patients, but not all individuals respond. The mechanisms underlying this response variability are poorly understood.
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