Open AccessRETRACTED: Association of Posttraumatic Stress Disorder With Reduced In Vivo Norepinephrine Transporter Availability in the Locus Coeruleus
Author(s) -
Robert H. Pietrzak,
JeanDominique Gallezot,
YuShin Ding,
Shannan Henry,
Marc N. Potenza,
Steven M. Southwick,
John H. Krystal,
Richard E. Carson,
Alexander Neumeister
Publication year - 2013
Publication title -
jama psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.531
H-Index - 365
eISSN - 2168-6238
pISSN - 2168-622X
DOI - 10.1001/jamapsychiatry.2013.399
Subject(s) - locus coeruleus , norepinephrine , norepinephrine transporter , posttraumatic stress , neuroscience , in vivo , association (psychology) , psychology , medicine , psychiatry , biology , genetics , central nervous system , dopamine , psychotherapist
Animal data suggest that chronic stress is associated with a reduction in norepinephrine transporter (NET) availability in the locus coeruleus. However, it is unclear whether such models are relevant to posttraumatic stress disorder (PTSD), which has been linked to noradrenergic dysfunction in humans.
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