Association of Adverse Experiences and Exposure to Violence in Childhood and Adolescence With Inflammatory Burden in Young People | Zendy

Line Jee Hartmann Rasmussen | Zendy; Terrie E. Moffitt | Zendy; Louise Arseneault | Zendy; Andrea Danese | Zendy; Jesper EugenOlsen | Zendy; Helen L. Fisher | Zendy; HonaLee Harrington | Zendy; Renate Houts | Zendy; Timothy Matthews | Zendy; Karen Sugden | Zendy; Benjamin Williams | Zendy; Avshalom Caspi | Zendy

Open Access

Association of Adverse Experiences and Exposure to Violence in Childhood and Adolescence With Inflammatory Burden in Young People

Author(s) -

Line Jee Hartmann Rasmussen,

Terrie E. Moffitt,

Louise Arseneault,

Andrea Danese,

Jesper EugenOlsen,

Helen L. Fisher,

HonaLee Harrington,

Renate Houts,

Timothy Matthews,

Karen Sugden,

Benjamin Williams,

Avshalom Caspi

Publication year - 2019

Publication title -

jama pediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.004

H-Index - 183

eISSN - 2168-6211

pISSN - 2168-6203

DOI - 10.1001/jamapediatrics.2019.3875

Subject(s) - medicine , supar , body mass index , cohort , biomarker , adverse childhood experiences , cohort study , adverse effect , pediatrics , plasminogen activator , urokinase receptor , psychiatry , mental health , biochemistry , chemistry

Childhood stress exposure is associated with inflammation as measured by C-reactive protein (CRP) and interleukin 6 (IL-6). However, findings are inconsistent and effect sizes are small. The addition of soluble urokinase plasminogen activator receptor (suPAR), a new biomarker of chronic inflammation, may improve measurement of stress-related inflammatory burden.

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