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Evaluation of Methylphenidate Safety and Maximum-Dose Titration Rationale in Attention-Deficit/Hyperactivity Disorder
Author(s) -
Cellina Ching,
Guy D. Eslick,
Alison Poulton
Publication year - 2019
Publication title -
jama pediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.004
H-Index - 183
eISSN - 2168-6211
pISSN - 2168-6203
DOI - 10.1001/jamapediatrics.2019.0905
Subject(s) - methylphenidate , medicine , jadad scale , attention deficit hyperactivity disorder , adverse effect , clinical trial , randomized controlled trial , medline , psychiatry , pediatrics , pharmacology , cochrane library , political science , law
Evidence on the titration of stimulant medications for attention-deficit/hyperactivity disorder (ADHD) is lacking. However, this lack of evidence has not prevented medication guidelines from specifying apparently arbitrary dose limitations, which could discourage clinicians from titrating methylphenidate to higher and, perhaps for some patients, more efficacious doses.

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