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Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze
Author(s) -
Kohei Hasegawa,
Jonathan M. Mansbach,
Yury A. Bochkov,
James E. Gern,
Pedro A. Piedra,
Cindy S. Bauer,
Stephen J. Teach,
Susan Wu,
Ashley F. Sullivan,
Carlos A. Camargo
Publication year - 2019
Publication title -
jama pediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.004
H-Index - 183
eISSN - 2168-6211
pISSN - 2168-6203
DOI - 10.1001/jamapediatrics.2019.0384
Subject(s) - medicine , bronchiolitis , wheeze , rhinovirus , immunology , sensitization , antibody , pediatrics , respiratory sounds , asthma , virus
Rhinovirus infection in early life, particularly with allergic sensitization, is associated with higher risks of developing recurrent wheeze and asthma. While emerging evidence links different rhinovirus species (eg, rhinovirus C) to a higher severity of infection and asthma exacerbation, to our knowledge, little is known about longitudinal associations of rhinovirus C infection during infancy with subsequent morbidities.

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