Association of Definition of Acute Kidney Injury by Cystatin C Rise With Biomarkers and Clinical Outcomes in Children Undergoing Cardiac Surgery
Author(s) -
Michael Zappitelli,
Jason H. Greenberg,
Steven G. Coca,
Catherine D. Krawczeski,
Simon Li,
Heather ThiessenPhilbrook,
Michael Bennett,
Prasad Devarajan,
Chirag R. Parikh
Publication year - 2015
Publication title -
jama pediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.004
H-Index - 183
eISSN - 2168-6211
pISSN - 2168-6203
DOI - 10.1001/jamapediatrics.2015.54
Subject(s) - medicine , acute kidney injury , cystatin c , renal function , creatinine , biomarker , kidney disease , receiver operating characteristic , odds ratio , supar , prospective cohort study , intensive care medicine , biochemistry , chemistry , urokinase receptor , urokinase
Research has identified improved biomarkers of acute kidney injury (AKI). Cystatin C (CysC) is a better glomerular filtration rate marker than serum creatinine (SCr) and may improve AKI definition.
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