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Author(s) -
Pranita D. Tamma,
Alison E. Turnbull,
Anthony Harris,
Aaron M. Milstone,
Alice J. Hsu,
Sara E. Cosgrove
Publication year - 2013
Publication title -
jama pediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.004
H-Index - 183
eISSN - 2168-6211
pISSN - 2168-6203
DOI - 10.1001/jamapediatrics.2013.196
Subject(s) - medicine , odds ratio , bacteremia , combination therapy , rifle , nephrotoxicity , renal function , acute kidney injury , propensity score matching , retrospective cohort study , kidney disease , surgery , antibiotics , kidney , history , archaeology , microbiology and biotechnology , biology
Definitive combination antibiotic therapy with a β-lactam and an aminoglycoside for the treatment of gram-negative bacteremia is commonly prescribed in pediatric patients; however, its efficacy and toxicity relative to β-lactam monotherapy are unknown.

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