Patterns of Treatment Failure and Postrecurrence Outcomes Among Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma After Chemoradiotherapy Using Modern Radiation Techniques | Zendy

Jonathan E. Leeman | Zendy; Jingao Li | Zendy; Xin Pei | Zendy; Praveen Venigalla | Zendy; Zachary S. Zumsteg | Zendy; Evangelia Katsoulakis | Zendy; Eitan Lupovitch | Zendy; Sean McBride | Zendy; C. Jillian Tsai | Zendy; Jay O. Boyle | Zendy; Benjamin R. Roman | Zendy; Luc G.T. Morris | Zendy; Lara Dunn | Zendy; Eric J. Sherman | Zendy; Nancy Y. Lee | Zendy; Nadeem Riaz | Zendy

Open Access

Patterns of Treatment Failure and Postrecurrence Outcomes Among Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma After Chemoradiotherapy Using Modern Radiation Techniques

Author(s) -

Jonathan E. Leeman,

Jingao Li,

Xin Pei,

Praveen Venigalla,

Zachary S. Zumsteg,

Evangelia Katsoulakis,

Eitan Lupovitch,

Sean McBride,

C. Jillian Tsai,

Jay O. Boyle,

Benjamin R. Roman,

Luc G.T. Morris,

Lara Dunn,

Eric J. Sherman,

Nancy Y. Lee,

Nadeem Riaz

Publication year - 2017

Publication title -

jama oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 8.846

H-Index - 99

eISSN - 2374-2445

pISSN - 2374-2437

DOI - 10.1001/jamaoncol.2017.0973

Subject(s) - medicine , radiation therapy , chemoradiotherapy , head and neck squamous cell carcinoma , hazard ratio , oncology , carcinoma , head and neck cancer , incidence (geometry) , cumulative incidence , surgery , cohort , confidence interval , optics , physics

Even though 15% to 50% of patients with head and neck squamous cell carcinoma (HNSCC) experience recurrence, relatively little is known regarding patterns of treatment failure and postrecurrence outcomes after chemoradiotherapy using modern radiation techniques (intensity-modulated radiotherapy [IMRT]). Recurrence patterns are significantly affected by variations in the quality of radiotherapy, which may confound findings from multicenter trials.

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