Open AccessAssociation of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy
Author(s) -
Michael L. Alosco,
Thor D. Stein,
Yorghos Tripodis,
Alicia S. Chua,
Neil W. Kowall,
Bertrand R. Huber,
Lee E. Goldstein,
Robert C. Cantu,
Douglas I. Katz,
Joseph Palmisano,
Brett Martin,
Jonathan D. Cherry,
Ian Mahar,
Ronald Killiany,
Michael D. McClean,
Rhoda Au,
Victor E. Alvarez,
Robert A. Stern,
Jesse Mez,
Ann C. McKee
Publication year - 2019
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2019.2244
Subject(s) - chronic traumatic encephalopathy , dementia , traumatic brain injury , medicine , leukoaraiosis , clinical dementia rating , white matter , neurology , concussion , psychology , physical therapy , psychiatry , poison control , disease , magnetic resonance imaging , injury prevention , emergency medicine , radiology
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repetitive head impacts, including those from US football, that presents with cognitive and neuropsychiatric disturbances that can progress to dementia. Pathways to dementia in CTE are unclear and likely involve tau and nontau pathologic conditions.
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