Open AccessAssociation of Bilateral Salpingo-Oophorectomy Before Menopause Onset With Medial Temporal Lobe Neurodegeneration
Author(s) -
Burcu Zeydan,
Nirubol Tosakulwong,
Christopher G. Schwarz,
Matthew L. Senjem,
Jeffrey L. Gunter,
Robert I. Reid,
Liliana Gazzuola Rocca,
Timothy G. Lesnick,
Carin Y. Smith,
Kent R. Bailey,
Val J. Lowe,
Rosebud O. Roberts,
Clifford R. Jack,
Ronald C. Petersen,
Virginia M. Miller,
Michelle M. Mielke,
Walter A. Rocca,
Kejal Kantarci
Publication year - 2018
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2018.3057
Subject(s) - temporal lobe , neurodegeneration , medicine , menopause , association (psychology) , audiology , gynecology , psychology , psychiatry , epilepsy , disease , psychotherapist
There is an increased risk of cognitive impairment or dementia in women who undergo bilateral salpingo-oophorectomy (BSO) before menopause. However, data are lacking on the association of BSO before menopause with imaging biomarkers that indicate medial temporal lobe neurodegeneration and Alzheimer disease pathophysiology.
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