Assessment of Extent and Role of Tau in Subcortical Vascular Cognitive Impairment Using 18F-AV1451 Positron Emission Tomography Imaging | Zendy

Hee Jin Kim | Zendy; Seongbeom Park | Zendy; Hanna Cho | Zendy; Young Kyoung Jang | Zendy; Jin San Lee | Zendy; Hyemin Jang | Zendy; Yeshin Kim | Zendy; Ko Woon Kim | Zendy; Young Hoon Ryu | Zendy; Jae Yong Choi | Zendy; Seung Hwan Moon | Zendy; Michael W. Weiner | Zendy; William J. Jagust | Zendy; Gil D. Rabinovici | Zendy; Charles DeCarli | Zendy; Chul Hyoung Lyoo | Zendy; Duk L. Na | Zendy; Sang Won Seo | Zendy

Open Access

Assessment of Extent and Role of Tau in Subcortical Vascular Cognitive Impairment Using ¹⁸F-AV1451 Positron Emission Tomography Imaging

Author(s) -

Hee Jin Kim,

Seongbeom Park,

Hanna Cho,

Young Kyoung Jang,

Jin San Lee,

Hyemin Jang,

Yeshin Kim,

Ko Woon Kim,

Young Hoon Ryu,

Jae Yong Choi,

Seung Hwan Moon,

Michael W. Weiner,

William J. Jagust,

Gil D. Rabinovici,

Charles DeCarli,

Chul Hyoung Lyoo,

Duk L. Na,

Sang Won Seo

Publication year - 2018

Publication title -

jama neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.298

H-Index - 231

eISSN - 2168-6157

pISSN - 2168-6149

DOI - 10.1001/jamaneurol.2018.0975

Subject(s) - positron emission tomography , hyperintensity , magnetic resonance imaging , white matter , cognitive impairment , psychology , neuroimaging , positron , cognition , medicine , nuclear medicine , neuroscience , radiology , physics , quantum mechanics , electron

Amyloid-β (Aβ), tau, and cerebral small vessel disease (CSVD), which occasionally coexist, are the most common causes of cognitive impairments in older people. However, whether tau is observed in patients with subcortical vascular cognitive impairment (SVCI), as well as its associations with Aβ and CSVD, are not yet established. More importantly, the role of tau underlying cognitive impairments in SVCI is unknown.

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