Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum | Zendy

Celeste M. Karch | Zendy; Natalie Wen | Zendy; Chun Chieh Fan | Zendy; Jennifer S. Yokoyama | Zendy; Naomi Kouri | Zendy; Owen A. Ross | Zendy; Günter U. Höglinger | Zendy; Ulrich Müller | Zendy; Raffaele Ferrari | Zendy; John Hardy | Zendy; Daniela Berg | Zendy; Patrick Sleiman | Zendy; Parastoo Momeni | Zendy; Christopher P. Hess | Zendy; Bruce L. Miller | Zendy; Manu Sharma | Zendy; Vivianna M. Van Deerlin | Zendy; Olav B. Smeland | Zendy; Ole A. Andreassen | Zendy; Anders M. Dale | Zendy; Rahul S. Desikan | Zendy

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Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum

Author(s) -

Celeste M. Karch,

Natalie Wen,

Chun Chieh Fan,

Jennifer S. Yokoyama,

Naomi Kouri,

Owen A. Ross,

Günter U. Höglinger,

Ulrich Müller,

Raffaele Ferrari,

John Hardy,

Daniela Berg,

Patrick Sleiman,

Parastoo Momeni,

Christopher P. Hess,

Bruce L. Miller,

Manu Sharma,

Vivianna M. Van Deerlin,

Olav B. Smeland,

Ole A. Andreassen,

Anders M. Dale,

Rahul S. Desikan

Publication year - 2018

Publication title -

jama neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.298

H-Index - 231

eISSN - 2168-6157

pISSN - 2168-6149

DOI - 10.1001/jamaneurol.2018.0372

Subject(s) - c9orf72 , frontotemporal dementia , amyotrophic lateral sclerosis , progressive supranuclear palsy , corticobasal degeneration , frontotemporal lobar degeneration , genetics , disease , dementia , medicine , neuroscience , psychology , biology , pathology

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by loss of upper and lower motor neurons. Although novel ALS genetic variants have been identified, the shared genetic risk between ALS and other neurodegenerative disorders remains poorly understood.

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